Claus Pietrzik: search on Z-Library

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1

Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer’s Mouse Model

Brandscheid, Carolin, Schuck, Florian, Reinhardt, Sven, Schäfer, Karl-Herbert, Pietrzik, Claus U., Grimm, Marcus, Hartmann, Tobias, Schwiertz, Andreas, Endres, Kristina

Journal:

Journal of Alzheimer's Disease

Year:

2017

Language:

english

File:

PDF, 459 KB

english, 2017

2

Total Synthesis of Methionine-Enkephalin

Prof. Dr. Wolfgang Voelter, Dipl.-Chem. Claus Bürvenich, Dipl.-Chem. Hans Horn, Dipl.-Chem. Hubert Kalbacher, Dipl.-Chem. Emanuel Pietrzik

Journal:

Angewandte Chemie International Edition

Year:

1976

Language:

english

File:

PDF, 224 KB

english, 1976

3

Synthesis of a potent photoreactive acidic γ-secretase modulator for target identification in cells

Andreas Rennhack, Thorsten Jumpertz, Julia Ness, Sandra Baches, Claus U. Pietrzik, Sascha Weggen, Bruno Bulic

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.68 MB

english, 2012

4

ENDOTHELIAL-LRP1 CLEARS MAJOR AMOUNTS OF ABETA 1-42 ACROSS THE BLOOD-BRAIN BARRIER

Storck, Steffen, Vandenbroucke, Roosmarijn E., Weggen, Sascha, Schwaninger, Markus, Bayer, Thomas, Pietrzik, Claus U.

Journal:

Alzheimer's & Dementia

Year:

2016

Language:

english

File:

PDF, 351 KB

english, 2016

5

P3-244

Waldron, Elaine A., Heilig, Catherine, Schweitzer, Andrea, Pietrzik, Claus U.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

6

LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer’s Disease

Van Gool, Bart, Storck, Steffen E., Reekmans, Sara M., Lechat, Benoit, Gordts, Philip L. S. M., Pradier, Laurent, Pietrzik, Claus U., Roebroek, Anton J. M.

Journal:

Molecular Neurobiology

Year:

2019

Language:

english

File:

PDF, 2.31 MB

english, 2019

7

Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway

Gil, So Young, Youn, Byung-Soo, Byun, Kyunghee, Huang, Hu, Namkoong, Churl, Jang, Pil-Geum, Lee, Joo-Yong, Jo, Young-Hwan, Kang, Gil Myoung, Kim, Hyun-Kyong, Shin, Mi-Seon, Pietrzik, Claus U., Lee, Bo

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

8

From Differentiation to Proliferation: The Secretory Amyloid Precursor Protein as a Local Mediator of Growth in Thyroid Epithelial Cells

Claus Ulrich Pietrzik, Jens Hoffmann, Kai Stober, Chun-Yan Chen, Christoph Bauer, Deborah A. C. Otero, Jean-Marc Roch and Volker Herzog

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.68 MB

english, 1998

9

The Functional Role of the Second NP X Y Motif of the LRP1 β-Chain in Tissue-type Plasminogen Activator-mediated Activation of N -Methyl-D-aspartate Receptors

Martin, Anne M., Kuhlmann, Christoph, Trossbach, Svenja, Jaeger, Sebastian, Waldron, Elaine, Roebroek, Anton, Luhmann, Heiko J., Laatsch, Alexander, Weggen, Sascha, Lessmann, Volkmar, Pietrzik, Claus

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 960 KB

english, 2008

10

P3-296 FE65 constitutes the functional link between the LDL receptor-related protein (LRP) and APP

Pietrzik, Claus U., Jaeger, Sebastian, Yoon, Il-Sang, Busse, Tracy, Weggen, Sascha, Koo, Edward H.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

11

Cellular prion protein participates in amyloid-β transcytosis across the blood–brain barrier

Pflanzner, Thorsten, Petsch, Benjamin, André-Dohmen, Bettina, Müller-Schiffmann, Andreas, Tschickardt, Sabrina, Weggen, Sascha, Stitz, Lothar, Korth, Carsten, Pietrzik, Claus U

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

12

Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation

Safina, Dina, Schlitt, Frederik, Romeo, Ramona, Pflanzner, Thorsten, Pietrzik, Claus U., Narayanaswami, Vasanthy, Edenhofer, Frank, Faissner, Andreas

Journal:

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

13

Concepts for the treatment of Alzheimer's disease: molecular mechanisms and clinical application

Claus Pietrzik, Christian Behl

Journal:

International Journal of Experimental Pathology

Year:

2005

Language:

english

File:

PDF, 572 KB

english, 2005

14

The role of lipoprotein receptors on the physiological function of APP

Timo Wagner, Claus U. Pietrzik

Journal:

Experimental Brain Research

Year:

2012

Language:

english

File:

PDF, 569 KB

english, 2012

15

P4-192: Mechanism of γ-secretase cleavage: Evidence for independent generation of Aβ42 and Aβ38 peptide species

Czirr, Eva, Cottrell, Barbara A., Serneels, Lutgarde, Leuchtenberger, Stefanie, Schubenel, Robert, Torpey, Justin W., Esselmann, Herrmann, Pietrzik, Claus U., Wiltfang, Jens, DeStrooper, Bart, Baumann

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

16

α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation

Sebastian Jäger, Stefanie Leuchtenberger, Anne Martin, Eva Czirr, Johanna Wesselowski, Marco Dieckmann, Elaine Waldron, Carsten Korth, Edward H. Koo, Michael Heneka, Sascha Weggen, Claus U. Pietrzik

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 714 KB

english, 2009

17

The physiological functions of the β-amyloid precursor protein APP

Ulrike C. Müller, Claus U. Pietrzik, Thomas Deller

Journal:

Experimental Brain Research

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

18

Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription

Elaine Waldron, Simone Isbert, Andreas Kern, Sebastian Jaeger, Anne M. Martin, Sébastien S. Hébert, Christian Behl, Sascha Weggen, Bart De Strooper, Claus U. Pietrzik

Journal:

Experimental Cell Research

Year:

2008

Language:

english

File:

PDF, 1.31 MB

english, 2008

19

The LepR-mediated leptin transport across brain barriers controls food reward

Di Spiezio, Alessandro, Sandin, Elvira Sonia, Dore, Riccardo, Müller-Fielitz, Helge, Storck, Steffen E., Bernau, Mareike, Mier, Walter, Oster, Henrik, Jöhren, Olaf, Pietrzik, Claus U., Lehnert, Hendri

Journal:

Molecular Metabolism

Year:

2017

Language:

english

File:

PDF, 4.35 MB

english, 2017

20

Discovery of γ-Secretase Modulators with a Novel Activity Profile by Text-Based Virtual Screening

Zettl, Heiko, Ness, Julia, Hähnke, Volker, Beher, Dirk, Jumpertz, Thorsten, Saric, Arman, Baumann, Karlheinz, Pietrzik, Claus U., Bulic, Bruno, Schneider, Gisbert, Weggen, Sascha

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

21

Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis

Marques, André R. A., Di Spiezio, Alessandro, Thießen, Niklas, Schmidt, Lina, Grötzinger, Joachim, Lüllmann-Rauch, Renate, Damme, Markus, Storck, Steffen E., Pietrzik, Claus U., Fogh, Jens, Bär, Julia

Journal:

Year:

2019

Language:

english

File:

PDF, 3.04 MB

english, 2019

22

Endothelial LRP1 – A Potential Target for the Treatment of Alzheimer’s Disease

Storck, Steffen E., Pietrzik, Claus U.

Journal:

Pharmaceutical Research

Year:

2017

Language:

english

File:

PDF, 3.03 MB

english, 2017

23

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

Thorsten Pflanzner, Maren C. Janko, Bettina André-Dohmen, Stefan Reuss, Sascha Weggen, Anton J.M. Roebroek, Christoph R.W. Kuhlmann, Claus U. Pietrzik

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 1.51 MB

english, 2011

24

LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State

Herr, Uta-Mareike, Strecker, Paul, Storck, Steffen E., Thomas, Carolin, Rabiej, Verena, Junker, Anne, Schilling, Sandra, Schmidt, Nadine, Dowds, C. Marie, Eggert, Simone, Pietrzik, Claus U., Kins, Ste

Journal:

Frontiers in Molecular Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.93 MB

english, 2017

25

The Metalloprotease Meprin β Is an Alternative β-Secretase of APP

Becker-Pauly, Christoph, Pietrzik, Claus U.

Journal:

Frontiers in Molecular Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.86 MB

english, 2017

26

Functional Role of the Low-Density Lipoprotein Receptor-Related Protein in Alzheimer’s Disease

Waldron, Elaine, Jaeger, Sebastian, Pietrzik, Claus U.

Journal:

Neurodegenerative Diseases

Year:

2006

Language:

english

File:

PDF, 196 KB

english, 2006

27

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

Jäckle, Felix, Schmidt, Frederike, Wichert, Rielana, Arnold, Philipp, Prox, Johannes, Mangold, Martin, Ohler, Anke, Pietrzik, Claus U., Koudelka, Tomas, Tholey, Andreas, Gütschow, Michael, Stirnberg,

Journal:

Biochemical Journal

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

28

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes

Peters, Florian, Scharfenberg, Franka, Colmorgen, Cynthia, Armbrust, Fred, Wichert, Rielana, Arnold, Philipp, Potempa, Barbara, Potempa, Jan, Pietrzik, Claus U., Häsler, Robert, Rosenstiel, Philip, Be

Journal:

The FASEB Journal

Year:

2019

File:

PDF, 4.24 MB

2019

29

Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing

Wagner, Timo, Dieckmann, Marco, Jaeger, Sebastian, Weggen, Sascha, Pietrzik, Claus U.

Journal:

Experimental Cell Research

Year:

2013

Language:

english

File:

PDF, 4.06 MB

english, 2013

30

Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains

Schmidt, Frederike, Müller, Miryam, Prox, Johannes, Arnold, Philipp, Schönherr, Caroline, Tredup, Claudia, Minder, Petra, Ebsen, Henriette, Janssen, Ottmar, Annaert, Wim, Pietrzik, Claus, Schmidt-Arra

Journal:

Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

31

Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model

Wagner, Sylvia, Zensi, Anja, Wien, Sascha L., Tschickardt, Sabrina E., Maier, Wladislaw, Vogel, Tikva, Worek, Franz, Pietrzik, Claus U., Kreuter, Jörg, von Briesen, Hagen, Deli, Maria A.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

32

Totalsynthese von Somatostatin, I / Total Synthesis of Somatostatin, I

Kalbacher, Hubert, Bürvenich, Claus, Fuchs, Stefan, Horn, Hans, Klingler, Wolfgang, Pietrzik, Emanuel, Zech, Karl, Voelter, Wolfgang

Journal:

Zeitschrift für Naturforschung B

Year:

1976

Language:

german

File:

PDF, 5.80 MB

german, 1976

33

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Weggen, Sascha, Eriksen, Jason L., Das, Pritam, Sagi, Sarah A., Wang, Rong, Pietrzik, Claus U., Findlay, Kirk A., Smith, Tawnya E., Murphy, Michael P., Bulter, Thomas

Journal:

Year:

2001

Language:

english

File:

PDF, 196 KB

english, 2001

34

O1-02-06: Genetic dissection of the PS1-ΔExon9 mutation and its attenuated response to Aβ42-lowering NSAIDs

Eva Czirr, Stefanie Leuchtenberger, Anna Schneider, Edward H. Koo, Claus U. Pietrzik, Sascha Weggen

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 73 KB

english, 2006

35

Presenilin is the molecular target of both acidic and non-acidic gamma-secretase modulators

Thorsten Jumpertz, Andreas Rennhack, Julia Ness, Sandra Baches, Heiko Zettl, Claus Pietrzik, Bruno Bulic

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

36

Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains

Schmidt, Frederike, Müller, Miryam, Prox, Johannes, Arnold, Philipp, Schönherr, Caroline, Tredup, Claudia, Minder, Petra, Ebsen, Henriette, Janssen, Ottmar, Annaert, Wim, Pietrzik, Claus, Schmidt-Arra

Journal:

Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

37

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

Storck, Steffen E., Hartz, Anika M.S., Bernard, Jessica, Wolf, Andrea, Kachlmeier, André, Mahringer, Anne, Weggen, Sascha, Pahnke, Jens, Pietrzik, Claus U.

Journal:

Brain, Behavior, and Immunity

Year:

2018

Language:

english

File:

PDF, 2.16 MB

english, 2018

38

Corrigendum: Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway

Gil, So Young, Youn, Byung-Soo, Byun, Kyunghee, Huang, Hu, Namkoong, Churl, Jang, Pil-Geum, Lee, Joo-Yong, Jo, Young-Hwan, Kang, Gil Myoung, Kim, Hyun-Kyong, Shin, Mi-Seon, Pietrzik, Claus U, Lee, Bon

Journal:

Nature Communications

Year:

2013

File:

PDF, 271 KB

2013

39

Amyloid Precursor-like Protein 1 Influences Endocytosis and Proteolytic Processing of the Amyloid Precursor Protein

Neumann, Stephanie, Schöbel, Susanne, Jäger, Sebastian, Trautwein, Anna, Haass, Christian, Pietrzik, Claus U., Lichtenthaler, Stefan F.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.16 MB

english, 2006

40

Mice are not Men: ADAM30 Findings Emphasize a Broader Look Towards Murine Alzheimer's Disease Models

Becker-Pauly, Christoph, Pietrzik, Claus U.

Journal:

Year:

2016

Language:

english

File:

PDF, 179 KB

english, 2016

41

Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments

Wild, Klemens, August, Alexander, Pietrzik, Claus U., Kins, Stefan

Journal:

Frontiers in Molecular Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.22 MB

english, 2017

42

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Simone Isbert, Katja Wagner, Simone Eggert, Andrea Schweitzer, Gerd Multhaup, Sascha Weggen, Stefan Kins, Claus U. Pietrzik

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 984 KB

english, 2012

43

Die Blut-Hirn-Schranke und ihre Rolle in der Alzheimer – Krankheit

Storck, Steffen E., Pietrzik, Claus U.

Journal:

Year:

2018

File:

PDF, 3.26 MB

2018

44

Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis

Sara M. Reekmans, Thorsten Pflanzner, Philip L. S. M. Gordts, Simone Isbert, Pascale Zimmermann, Wim Annaert, Sascha Weggen, Anton J. M. Roebroek, Claus U. Pietrzik

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

45

Presenilin-1 (PS1) and amyloid precursor protein (APP) mutations present in mouse models of Alzheimer's disease in their response to γ-secretase inhibitors and modulators

Lehmann, Stefanie, Bruening, Tanja, Ness, Julia, Czirr, Eva, Bulic, Bruno, Pietrzik, Claus U., Weggen, Sascha

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

46

P3-247

Jaeger, Sebastian, Rogge, Barbara S., Weggen, Sascha, Koo, Edward H., Pietrzik, Claus U.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

47

LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

Tucher, Joanna, Linke, Dennis, Koudelka, Tomas, Cassidy, Liam, Tredup, Claudia, Wichert, Rielana, Pietrzik, Claus, Becker-Pauly, Christoph, Tholey, Andreas

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 1.99 MB

english, 2014

48

Functional Role of Lipoprotein Receptors in Alzheimers Disease

Pietrzik, Claus, Jaeger, Sebastian

Journal:

Current Alzheimer Research

Year:

2008

Language:

english

File:

PDF, 315 KB

english, 2008

49

Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer’s disease

Harshvardhan Rolyan, Ann Caroline Feike, Ajeet Rijal Upadhaya, Andreas Waha, Tom Van Dooren, Christian Haass, Gerd Birkenmeier, Claus U. Pietrzik, Fred Van Leuven, Dietmar Rudolf Thal

Journal:

Journal of Neural Transmission

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

50

Inhibitors of Rho-kinase modulate amyloid-β (Aβ) secretion but lack selectivity for Aβ42

Stefanie Leuchtenberger, Markus P. Kummer, Thomas Kukar, Eva Czirr, Nicole Teusch, Sarah A. Sagi, Rebecca Berdeaux, Claus U. Pietrzik, Thomas B. Ladd, Todd E. Golde, Edward H. Koo, Sascha Weggen

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 642 KB

english, 2006

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